This website is dedicated to the millions of thyroid patients who are being ignored and left to suffer unnecessarily, and to healthcare practitioners, who want to better serve those patients.

Autoimmune Thyroiditis

Autoimmune thyroiditis can be healed using a functional medicine approach. Here, we explore some of the approaches we use in these circumstances.

When working to identify the root cause, we keep asking questions until we find the answer. So now we know that hypothyroidism occurs because of thyroid destruction and that thyroid destruction occurs because of self-antibodies, why does the immune system make self-antibodies?

Molecular Mimicry

In addition to oxidative damage, immune cells may also be attracted to the thyroid as a result of a viral/bacterial infection that either infects the thyroid cells and needs to be cleared, or look similar to the thyroid cells, causing ‘Molecular Mimicry’.

An antigen is a substance that evokes the production of antibodies. Molecular Mimicry is the theory that bacterial cells or other microbes triggers off a similar appearance to the cells that make up parts of our physiology or self-antigens. When an infection occurs, these infectious cells are recognised as foreign. This is really great for getting rid of infections, sometimes the immune system targets proteins in infectious cells and resemble the proteins in our own cells. This inadvertently causes a cross-reaction with our self-antigens, i.e. our own cells. This case of mistaken identity is thought to trigger the start of autoimmunity.

In our experience, the biggest examples of this are viral infections. Various pathogens have been suggested to play a role in the development of Hashimoto’s ranging from bacteria to viruses to fungi and parasites. Often, it is not merely one type of bacteria or virus that triggers that autoimmune process, but a combination of pathogens present:

Bug X + Bug Y = Disease Z

Which bacterial and viruses have been associated with triggering autoimmune thyroiditis ?

A variety of bacterial infections have been implicated in triggering autoimmune thyroiditis including Helicobacter pylori (the same bacteria that causes ulcers) and Yersinia enterocolitica. Antibodies to Yersinia in people with Hashimoto’s have been found 14 times more often than in people without Hashimoto’s. Additionally, in our experience, the biggest single viral-cause in Hashimoto’s is Epstein Barr virus, regardless whether someone has had glandular fever or not in the past.

In addition to the foregoing and genetic susceptibility and other triggers, there is a third piece of the puzzle that must be present for Hashimoto’s or Graves’ to develop. This common link is present in all autoimmune conditions and gets closer to the root cause of the development of autoimmunity: increased intestinal permeability, aka, leaky gut.

So what does the gut have to do with the immune system and autoimmunity?

Everything! It is the intestinal lining that prevents autoimmunity.

Researchers have found, in addition to digesting and absorbing nutrients and keeping water and electrolyte balance, the intestine is also responsible for helping the immune system recognise foreign invaders from self-antigens, thus facilitating the control of pathogens preventing autoimmune reactions.

What exactly is leaky gut?

Read More HERE

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