Coeliac Disease And The Thyroid Connection – Antibodies
In an article in ‘The Australian Coeliac (Sept 08)’ Dr Jason Tye-Din from the Royal Melbourne Hospital states that a person must be willing to resume a normal diet (that contains gluten) for at least 6 weeks to enable meaningful test results. He mentioned that adequate consumption of gluten can be achieved by consuming 4 slices of bread per day for 6 wks in adults. More info about the tests that are necessary to screen for Coeliac Disease (including test to measure antibodies to transglutaminase (transglutaminase antibodies or “tTG”) and gliadin (anti-gliadin antibodies or “AGA”) + other tests can be found by referring to Dr Tye-Din’s article.
It as been observed that individuals with Celiac disease (gluten intolerance) also have thyroid problems. In the new research scientists tracked down the link by establishing that auto-immune antibodies against transglutaminase (a Celiac problem) latch on to thyroid tissue and rev up thyroid autoantibodies (TPO antithyroperoxidase antibodies), leading to thyroid tissue damage.
Tissue Transglutaminase Antibodies in Individuals with Celiac Disease Bind to Thyroid Follicles and Extracellular Matrix and May Contribute to Thyroid Dysfunction