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Coeliac Disease And The Thyroid Connection – Antibodies

In an article in ‘The Australian Coeliac (Sept 08)’ Dr Jason Tye-Din from the Royal Melbourne Hospital states that a person must be willing to resume a normal diet (that contains gluten) for at least 6 weeks to enable meaningful test results. He mentioned that adequate consumption of gluten can be achieved by consuming 4 slices of bread per day for 6 wks in adults. More info about the tests that are necessary to screen for Coeliac Disease (including test to measure antibodies to transglutaminase (transglutaminase antibodies or “tTG”) and gliadin (anti-gliadin antibodies or “AGA”) + other tests can be found by referring to Dr Tye-Din’s article.

Coeliac Australia

It as been observed that individuals with Celiac disease (gluten intolerance) also have thyroid problems. In the new research scientists tracked down the link by establishing that auto-immune antibodies against transglutaminase (a Celiac problem) latch on to thyroid tissue and rev up thyroid autoantibodies (TPO antithyroperoxidase antibodies), leading to thyroid tissue damage.

Further information:

http://online.liebertpub.com/doi/abs/10.1089/thy.2008.0110
Tissue Transglutaminase Antibodies in Individuals with Celiac Disease Bind to Thyroid Follicles and Extracellular Matrix and May Contribute to Thyroid Dysfunction

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