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Insulin Resistance its association with Clinical Hypothyroidism

Insulin Resistance its association with Clinical Hypothyroidism

Glucose and insulin resistance appears to go hand in hand with thyroid resistance

http://jcem.endojournals.org/cgi/content/abstract/91/12/4930
Conclusions: In hypothyroidism: 1) glucose uptake in muscle and adipose tissue is resistant to insulin; 2) suppression of lipolysis by insulin is not impaired; and 3) hypertriglyceridemia is due to decreased clearance by the adipose tissue.

http://www.eje-online.org/cgi/content/abstract/160/5/785
In dogs as human studies of this are scarce according to the above study

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WXN-4TK7XFG-7&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=849d2e9fadb6cd1587cdaaec6559792b In dogs as human studies of this are scarce according to the above study, which showed that canine hypothyroidism is associated with increased serum leptin and insulin concentrations, neither of which may be attributed to obesity alone

http://www.ncbi.nlm.nih.gov/pubmed/3176815 Characterization of the insulin resistance of glucose utilization in adipocytes from patients with hyper- and hypothyroidism.

http://www.ncbi.nlm.nih.gov/pubmed/17628531?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Atherogenic diet induced diabetes mellitus: involvement of thyroid hormones.

http://care.diabetesjournals.org/content/30/12/3128.abstractImpaired – Postprandial Blood Flow in Adipose Tissue May Be an Early Marker of Insulin Resistance in Type 2 Diabetes

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