Synthetic Thyroxine is NOT the same as Natural Thyroxine
Synthroid (levothyroxine sodium), as the name implies, is NOT natural, is NOT bio-equivalent to the hormone thyroxine (T4) produced by the human thyroid, but rather is a SYNTHETIC hormone-like substance with radically different structural and functional properties.
Hormones, like all biomolecules, obey a fundamental structure-function complementarity, i.e. form and function are inseparably connected. As you can see from the chemical skeletons above, the two substances are NOT identical. The glaring differences in their respective chemical/molecular make-ups will simultaneously reflect functional/behavioral differences. Not a single cell in the human body can be ‘tricked’ into considering them bio-equivalent, even if the conventional medical establishment reiterates endlessly the manufacturer’s marketing claims that they are treated identically by the human body. (Sadly, MEDLINE PLUS, a service of the U.S. National Library of Medicine and The National Institutes of Health convey that they are not different: http://www.nlm.nih.gov/medlineplus/druginfo/meds/a682461.html
It doesn’t take a Ph.D in pharmacology or biochemistry to understand that when you force a genetically-modified form of E. Coli bacteria to secrete a human-like hormone, subtle (if not also not so subtle) differences will emerge. It also doesn’t take a whole lot of intelligence to figure out that IF the pharmaceutical industry created a thyroid drug truly IDENTICAL to the natural hormone it is designed to replace, it would not be able to lay claim to a proprietary, patentable and thereby profitable product, i.e. there really is no reward in reproducing exactly the good works of God/Nature.
And yet the problem with creating synthetic, tinkered-with analogues of natural substances is that they almost invariably come with a set of monstrous unintended consequences. Indeed, research published in 2010 in the Archives of Pharmaceutical Research shows that levothyroxine preparations are widely contaminated with a "mirror image" stereoiosmer called dextro-thyroxine at a level as high as 1-6% by dry weight. D-thyroxine violates the left-handed ‘chirality’ of natural thyroxine and is a powerful, cardiotoxic endocrine disruptor. This may explain why so many patients who have had their TSH levels suppressed (i.e.normalized) with synthetic T4 feel like the **** their drugs were grown in (E.Coli).
Lack of Synthroid is NOT the cause of any thyroid problem. Poisoning, common food intolerances (e.g. wheat/dairy), adrenal fatigue and nutrient deficiency are the cause of hypothyroidism in the vast majority of cases, so let’s get back to the work of figuring out how to address the problem naturally.
Below http://www.greenmedinfo.com/blog/synthroid-levothyroxine-sodium-not-thyroxine is research I have been collecting on the topic of hypothyroidism from a naturopathic perspective. Take close note of the 33 problem substances listed below, as it is vitally important that people understand ‘being poisoned’ (and resultant nutrient depletions) is likely a major contributing factor to suboptimal thyroid function. Remove the cause, as they say, and you have the cure!